What does the term "secondary intention" refer to in wound healing?

The term "secondary intention" in wound healing specifically refers to the process where a wound heals through the formation of granulation tissue and epithelialization, typically resulting in more extensive healing compared to wounds that heal by primary intention. This method allows the wound to close from the bottom and sides, making it a slower process and often leaving more scar tissue due to the larger area of tissue loss.

When healing occurs by secondary intention, the wound is usually left open and fills with granulation tissue over time. This can result in a thicker scar since the tissue regeneration is done through secondary layers of newly formed tissue. Unlike primary intention, where wound edges are closely approximated and minimal scarring occurs, secondary intention involves a wider area of healing which can result in a more significant scar.

Other options do not specifically define secondary intention. While options regarding minimal scarring or healing without complications are more relevant to primary intention, the significant inflammatory response can occur in both types of healing processes. Therefore, the correct understanding aligns with the broader context of secondary intention focusing on the layered healing of the wound.